Creagen Biosciences Inc.

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Medchem Analytical Other Services

BioDiverseCores Optimized Molecular Entities

Drug Discovery Research Training (DDRT)

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ADMET and Pharmacokinetic Studies:
Hits from screening campaigns will be confirmed through sensitive biological assays to determine whether the compound is effective in inhibiting or activating the molecular target under study. We also provide pharmacokinetic data, including metabolic and chemical stability, membrane permeability, solubility, inhibition of major metabolic enzymes and mutagenicity.

Natural product Scaffolds:
Synthesis of natural product scaffolds and small set of (20-40) optimized libraries containing natural product scaffolds.

Building Block Synthesis:
Design and synthesis of building blocks/scaffolds with multiple reactive sites from milligram to multi grams

Lead Design:
Design and synthesis of optimized small targeted libraries for lead generation. Active Pharmaceutical Intermediates: Design and synthesize optimized small molecule libraries around API’s.

File enrichment libraries:
Generation of libraries of compounds according to customers file enrichment needs.

Solid phase synthesis:
Screening library synthesis on solid support.

Process optimization:
Expedite the transfer of process from bench top to poilet plants using combinatorial technology.

Company Profile

CreaGen Biosciences, Inc. is located in Woburn, MA, on the near north side of the Greater Boston Area. Boston is one of the primary hubs in the world for life sciences research.
(Corporate Fact Sheet)
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News

2009
Recent Developments
1) Press Release (PDF)
2) Patent publication

Dr. Rajur chaired the medicinal chemistry symposium of the Northeastern section of American Chemical Society, Marriott Hotel, Burlington, MA, on September 10th, 2009. Symposium title "Recent Developments in Neurodegenerative diseases”

The Boston Society and NESACS applied pharmaceutical sciences and medicinal chemistry symposium titled"Frontiers in Strategies and Technologies to enrich pharmaceutical pipelines” held on
May 21-22, 2009 at the Merck Research Laboratories Boston Amphitheater, Boston, MA. was Hosted and co-sponsored in part by CreaGen Biosciences, Inc.

3rd Annual Advances In Chemical Sciences Symposium held on April 10, 2009 at the Royal Sonesta Hotel in Cambridge, MA. was Hosted and co-sponsored in part by CreaGen Biosciences, Inc.

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