Creagen Biosciences Inc.

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Optimized Molecular Entities™ (OMEs™)

Optimized molecular entities are target-relevant small molecules whose drug-like properties have been optimized for preclinical screening. These OMEs have been derived from cores from our BDC collections. We apply our in-depth knowledge to design and synthesize these molecules. We believe that OMEs have a greater likelihood of success to become development candidates. Currently, we have a 100-membered library that is available for immediate pilot screening. CreaGen continues to produce new libraries and make them available for partners screening.

Capabilities

• Rapid design and synthesis of OME libraries for Lead Discovery and Optimization
• Cycle times of 3-4 weeks from design to delivery
• All compounds purified by reverse phase HPLC
• All compounds quantified and characterized by LCMS (UV214, UV254) and NMR spectroscopy

Capacity

• 10,000 OME library compounds annually
• Typical quantities of 5-10 mg
• Supplied in DMSO solution (96-well plates) or in powder form

Please contact our R & D Coordinator for more information.

Company Profile

CreaGen Biosciences, Inc. is located in Woburn, MA, on the near north side of the Greater Boston Area. Boston is one of the primary hubs in the world for life sciences research.
(Corporate Fact Sheet)
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News

2009
Recent Developments
1) Press Release (PDF)
2) Patent publication

Dr. Rajur chaired the medicinal chemistry symposium of the Northeastern section of American Chemical Society, Marriott Hotel, Burlington, MA, on September 10th, 2009. Symposium title "Recent Developments in Neurodegenerative diseases”

The Boston Society and NESACS applied pharmaceutical sciences and medicinal chemistry symposium titled"Frontiers in Strategies and Technologies to enrich pharmaceutical pipelines” held on
May 21-22, 2009 at the Merck Research Laboratories Boston Amphitheater, Boston, MA. was Hosted and co-sponsored in part by CreaGen Biosciences, Inc.

3rd Annual Advances In Chemical Sciences Symposium held on April 10, 2009 at the Royal Sonesta Hotel in Cambridge, MA. was Hosted and co-sponsored in part by CreaGen Biosciences, Inc.

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