Creagen Biosciences Inc.

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BioDiverseCores Optimized Molecular Entities

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BioDiverseCores™ (BDCs ™):

CreaGen’s BDC program has collections of novel natural product and natural product-like scaffolds. Many of these scaffolds are target relevant cores that are designed to produce small molecule IP. These low molecular weight compounds are ideal for fragment-based screening. These cores have been designed with multiple diversity points to facilitate rapid synthesis of analogs that will provide SAR information. The multiple diversity points can also be be utilized to improve the pharmacokinetic properties of the target molecules such as solubility, bioavailability, selectivity and potency. CreaGen currently has 100 scaffolds in its BDC collection and continues to add approximately 25 new scaffolds per quarter. Our partners will have immediate access to our collections on a non-exclusive basis to develop potential new starting points for research programs.

Company Profile

CreaGen Biosciences, Inc. is located in Woburn, MA, on the near north side of the Greater Boston Area. Boston is one of the primary hubs in the world for life sciences research.
(Corporate Fact Sheet)
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News

2009
Recent Developments
1) Press Release (PDF)
2) Patent publication

Dr. Rajur chaired the medicinal chemistry symposium of the Northeastern section of American Chemical Society, Marriott Hotel, Burlington, MA, on September 10th, 2009. Symposium title "Recent Developments in Neurodegenerative diseases”

The Boston Society and NESACS applied pharmaceutical sciences and medicinal chemistry symposium titled"Frontiers in Strategies and Technologies to enrich pharmaceutical pipelines” held on
May 21-22, 2009 at the Merck Research Laboratories Boston Amphitheater, Boston, MA. was Hosted and co-sponsored in part by CreaGen Biosciences, Inc.

3rd Annual Advances In Chemical Sciences Symposium held on April 10, 2009 at the Royal Sonesta Hotel in Cambridge, MA. was Hosted and co-sponsored in part by CreaGen Biosciences, Inc.

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